Monograph of Diethylcarbamazine
Introduction Diethylcarbamazine (DEC) is a synthetic antihelminthic agent widely employed in the treatment of filarial infections, particularly lymphatic filariasis and onchocerciasis. Its…
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Monograph of Ivermectin
Introduction Definition and Overview Ivermectin is a semi‑synthetic derivative of avermectin B1a, belonging to the macrocyclic lactone class of antiparasitic agents. It…
Monograph of Mebendazole
Introduction/Overview Mebendazole is a broad‑spectrum benzimidazole anthelmintic that has been employed for over six decades to treat a variety of helminthic infections.…
Monograph of Quinine
Introduction Quinine is a naturally occurring quaternary ammonium alkaloid extracted from the bark of the cinchona tree species, predominantly Cinchona officinalis and…
Monograph of Primaquine
Introduction Primaquine is a synthetic 8-aminoquinoline derivative widely employed in the treatment of malaria, particularly for the radical cure of Plasmodium vivax…
Ritonavir Monograph
Introduction Definition and Overview Ritonavir is an oral antiretroviral agent that functions primarily as a potent inhibitor of the cytochrome P450 3A4…
Monograph of Efavirenz
Introduction Efavirenz is a non‑nucleoside reverse transcriptase inhibitor (NNRTI) that has played a pivotal role in the management of human immunodeficiency virus…
Tenofovir Monograph
Introduction Tenofovir is a nucleotide reverse‑transcriptase inhibitor (NRTI) that has become a cornerstone in the treatment of human immunodeficiency virus (HIV) infection…
Monograph of Lamivudine
Introduction Definition and Overview Lamivudine (3‑(3‑methyl‑2‑hydroxypropyl)‑1‑β‑D‑ribofuranosyl‑2‑thio‑pyrimidine) is a nucleoside analog reverse transcriptase inhibitor (NRTI) employed primarily in the treatment of human immunodeficiency…
Monograph of Oseltamivir
Introduction Oseltamivir is a synthetic antiviral agent classified as a neuraminidase inhibitor, designed to impede the release of influenza A and B…