Monograph of Artemisinin
Introduction Artemisinin is a sesquiterpene lactone containing a peroxide bridge, isolated from the plant Artemisia annua. Its discovery marked a pivotal advance…
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Monograph of Chloroquine
Introduction Chloroquine is a synthetic 4-aminoquinoline compound that has been a cornerstone of antimalarial therapy since its introduction in the mid‑20th century.…
Monograph of Zidovudine
Introduction Zidovudine, also known as AZT (azidothymidine), represents one of the pioneering nucleoside analog reverse transcriptase inhibitors (NRTIs) employed in the management…
Monograph of Acyclovir
Introduction Acyclovir is a nucleoside analogue that functions as a selective inhibitor of viral DNA synthesis. It has become a cornerstone of…
Monograph of Fluconazole
Introduction / Overview Brief Introduction Fluconazole is a triazole antifungal agent that has been a cornerstone of systemic fungal therapy since its…
Monograph of Amphotericin B
Introduction otericin B is a polyene macrolide antifungal agent that has maintained a pivotal role in the treatment of severe systemic mycoses…
Dapsone Monograph
Introduction Dapsone, chemically known as 4‑(sulfapyridine‑2‑yl)‑2‑nitro‑1,3‑benzene disulfonamide, is a sulfone derivative that has been employed for more than six decades as an…
Monograph of Pyrazinamide
Introduction Definition and Overview Pyrazinamide (PZA) is a short‑acting, orally administered antitubercular agent that belongs to the pyrazinamide class of compounds. It…
Monograph of Isoniazid
Introduction Isoniazid (INH) is a first‑line antitubercular agent that has been instrumental in the control of tuberculosis (TB) worldwide. It is a…
Monograph of Rifampicin
Introduction Definition and Overview Rifampicin, also known as rifampin, is a broad-spectrum bactericidal antibiotic belonging to the rifamycin class. It exerts its…